Last year the Philadelphia Eagles gave us a preview of what it is like to field a team with a much-depleted roster due to injury. Coach Pederson did a great job of successfully managing games with practice squad players. Teams that can emulate that kind of coaching will be at an advantage. The lack of preseason games will make for interesting result I will be picking a winner without the spread for each game and I will be picking three games with the spread. I am really looking forward to this season, after thinking back in April that the 2020 season was in serious jeopardy. Have a great Sunday !
| Favorites | Spread | Dogs | Comment | Pick | Pick with spread | |
| At Chiefs | 9 | Texans | Chiefs will start defending their Superbowl title by beating the Texans. Texans are good but not ready for the Chiefs. | Chiefs | ||
| At Bills | 6.5 | Jets | The bills have added some key elements, the Jets have too many holes to fill. Stefon Diggs will add a new dimension to the offense. Bills already have a solid defense. The Jets will not be up for this challenge. | Bills | Bills | |
| At Vikings | 2.5 | Packers | The Packers beat the Vikings twice last year. Not going to happen this year. Vikings will win this one by more than 2.5 points. | Vikings | Vikings | |
| Eagles | 6 | At Redskins | The Washington Football has improved, good defense, Haskins will be better. The Eagles will win and cover. | Eagles | Eagles | |
| At Ravens | 8 | Browns | Ravens!!! | Ravens | ||
| Colts | 7.5 | At Jaguars | Colts will win. First of many losses for the Jaguars. | Colts | ||
| Raiders | 3 | At Panthers | I don’t think the Panthers are ready to win yet. Raiders win a close one. | Raiders | ||
| At Lions | 2.5 | Bears | Don’t like the way the Bears played last year. The Lions will start the year with a roar and win. | Lions | ||
| Seahawks | 1.5 | At Falcons | Falcons finished strongly year. They will get off to a winning start this and defeat the Seahawks. | Falcons | ||
| At Patriots | 6.5 | Dolphins | Miami is much improved, but the Brady-less Patriots will win at home. | Patriots | ||
| Chargers | 3.5 | At Bengals | Will Joe Burrow win in his first start? Chargers have an excellent defense. I’m going with the Chargers. | Chargers | ||
| At 49ers | 7 | Cardinals | It will be an interesting game, I can’t see the 49ers lose their home opener. | 49ers | ||
| At Saints | 3.5 | Bucs | The Brady era with the Buccaneers starts with a loss. | Saints | ||
| Cowboys | 3 | At Rams | The Cowboys are looking good. Rams have a lot to prove after missing the postseason last year. Rams will win the one. | Rams | ||
| Steelers | 5.5 | At Giants | Not opening in Dallas…. Giants win! | Giants | ||
| Titans | 1 | At Broncos | Titans will run the ball, play great defense and win. | Titans | ||